Assistant Professor of Medicine

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Approval of remote and hybrid work is not guaranteed regardless of work location.For additional information on remote work at Penn State, seeNotice to Out of State Applicants.

This is a term position; length of the term will be discussed during the interview process. Continuation past the termlengthdiscussed willbebasedonuniversityneed,performance,and/oravailabilityoffunding.

POSITION SPECIFICS

Position: Assistant Professor of Medicine (Non-Tenure)

Department: Department of Medicine, Penn State College of Medicine

Position Summary

Penn State College of Medicine (PSCOM) is seeking a highly skilled scientist to serve as Director of the Human iPSC & CRISPR Editing Core, a new shared research resource supporting translational and precision medicine research across the COM and Penn State Health (PSH).

This position is a dual-role appointment, with 50% effort dedicated to directing the iPSC & CRISPR Editing Core and 50% effort dedicated to research laboratory management within the Department of Medicine (DOM). This role provides an opportunity to build and lead a core facility while maintaining close engagement in active translational research programs.

Primary Responsibilities

Director, Human iPSC & CRISPR Editing Core

• Establish, lead, and operate the Human iPSC & CRISPR Editing Core.
• Oversee generation, propagation, differentiation, and characterization of human iPSCs, including iPSC-derived cardiomyocytes.
• Develop and implement CRISPR/Cas9-based genome editing approaches (knock-in, knock-out, variant modeling).
• Build and manage scalable and high-throughput iPSC-based experimental platforms.
• Provide scientific consultation to investigators on experimental design and feasibility.
• Collaborate with faculty across PSCOM, PSH, and the Department of Molecular and Precision Medicine, including alignment with organoid and precision medicine initiatives.
• Develop and maintain SOPs, quality control standards, and reproducibility practices.
• Oversee core operations, including scheduling, training, and cost-recovery activities.
• Contribute technical expertise to grant applications and progress reports.
• Ensure compliance with institutional biosafety, regulatory, and research policies.

Research Laboratory Management – Department of Medicine

• Serve as senior laboratory manager for a translational cardiovascular research laboratory.
• Oversee daily laboratory operations, including personnel supervision, purchasing, budgeting, and compliance.
• Support and execute experimental workflows involving human iPSC-derived models, genome editing, and functional assays.
• Train and mentor laboratory staff and trainees in advanced cell biology and genome editing techniques.
• Ensure continuity, efficiency, and rigor in laboratory operations and research activities.

Required Qualifications

• PhD or equivalent doctoral degree in a relevant biomedical discipline.
• Demonstrated expertise in:
  • Human iPSC generation, maintenance, and differentiation
  • CRISPR/Cas9 genome editing technologies
• experience managing complex laboratory operations.
• Strong organizational, communication, and leadership skills.
• Ability to work collaboratively in a multidisciplinary academic research environment.

Preferred Qualifications

• Prior experience leading or contributing to a core facility or shared research resource.
• Expertise in iPSC-derived cardiomyocytes and cardiovascular disease modeling.
• Experience supporting NIH- or VA-funded research programs.
• Familiarity with core facility cost-recovery models.

Additional Information

This position offers the opportunity to play a key leadership role in building PSCOM’s translational research infrastructure while remaining closely engaged in discovery science within the DOM.

BACKGROUND CHECKS/CLEARANCES

Employment with the University will require successful completion of background check(s) in accordance with University policies.

BENEFITS

Penn State provides a competitive benefits package for full-time employees designed to support both personal and professional wellbeing. In addition to comprehensive medical, dental, and vision coverage, employees enjoy robust retirement plans. One of the standout benefits is the generous 75% tuition discount, available to employees as well as eligible spouses and children.

For more detailed information, please visit ourBenefits Page. (Note: For Postdoctoral benefits, please see our Postdoctoral Benefits page.)

CAMPUS SECURITY CRIME STATISTICS

Pursuant to the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act and the Pennsylvania Act of 1988, Penn State publishes a combined Annual Security and Annual Fire Safety Report (ASR). The ASR includes crime statistics and institutional policies concerning campus security, such as those concerning alcohol and drug use, crime prevention, the reporting of crimes, sexual assault, and other matters. The ASR is available for review here.

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