Associate Professor – Hematologic Malignancies

Join the forefront of groundbreaking research at the Beckman Research Institute ofCity of Hope, where we’re changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

City of Hope has an opening for an Associate Research Professor. The Associate Research Professor will serve as an independent investigator within the translational hematopathology program led by Dr. M. James You. The successful candidate will develop a focused research program aligned with the laboratory’s core themes, including leukemic stem cell biology, tumor suppressor pathways, cancer metabolism, and genetically defined models of leukemia and lymphoma. The Associate Professor will be expected to secure independent extramural funding, publish high-impact research, and contribute to translational initiatives, including biomarker discovery and clinical trial correlative science. The position involves mentoring trainees and junior scientists, supervising research staff, and serving as a key academic and operational leader in the laboratory. The Associate Professor will also engage in interdepartmental collaboration through Beckman Research Institute programs, disease-focused research teams, and institutional strategic initiatives, advancing scientific discovery and translating it into meaningful innovations in cancer diagnostics and therapy.

For more information about Dr. You’s lab, please visit here.

As a successful candidate, you will:

• Lead and sustain an independent research program focused on hematologic malignancies, aligned with the laboratory’s mission to advance discoveries in tumor suppressor biology, leukemia stem cell mechanisms, cancer metabolism, and translational pathology.

• Design and execute hypothesis-driven studies using genetically engineered models, patient-derived samples, and multi-omic platforms to uncover therapeutic vulnerabilities and molecular biomarkers in leukemia and lymphoma.

• Serve as principal investigator on extramurally funded grants; write and submit research proposals that build upon and complement existing programmatic support, contributing to the long-term scientific and financial sustainability of the program.

• Mentor and supervise graduate students, postdoctoral fellows, junior faculty, and technical staff to ensure scientific rigor, data reproducibility, and career development in alignment with City of Hope’s educational mission.

• Drive translational research initiatives by leading correlative science for clinical trials, validating diagnostic or predictive biomarkers, and collaborating with clinicians to align research outcomes with patient care goals.

• Collaborate with shared resource cores (e.g., Genomics, Cytometry, Analytical Pharmacology) and institutional research centers to integrate advanced methodologies that accelerate discovery and enhance scientific innovation.

• Contribute to the scientific community through authorship of high-impact publications, presentations at national and international meetings, and participation in academic symposia, peer review, and grant panels.

Your qualifications should include:

• PhD, MD, or Master’s degree in a relevant biomedical field (or commensurate experience) with a minimum of 3 years of hands-on experience in a clinical or research laboratory focused on hematologic malignancies, molecular pathology, or flow cytometry.

• Demonstrated expertise in data analysis and immunophenotyping; experience with cell sorting is highly desirable.

• Proven ability to design and execute experiments using mouse models, primary human samples, and genomic profiling tools (e.g., NGS, RNA-seq).

• Demonstrated leadership in mentoring junior staff, managing laboratory operations, and coordinating with clinical and pathology personnel to meet research and project deadlines.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.