Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Category: AcademicJob Description:Grade UE07: £40,497 – £48,149 per annum pro-rata if part-timeCMVM / Institute for Regeneration and Repair / Centre for Inflammation ResearchFull-time: 35 hours per weekFixed-term: 18 months – appointment above step 3 of Grade UE07 may necessitate a reduction of contract length due to a fixed budget.We are looking for an enthusiastic Postdoctoral Research Fellow to work in a research group studying the role of senescence in cardio-renal disease.This post is advertised as full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.The Opportunity:The candidate will work with human cell lines and tissue, as well as murine models to study the role of senescence in cardio-renal disease. Using in-house RNA sequencing datasets, the post-holder will discover common human renal and cardiac senescence biomarkers. They will also test the potential of spatial transcriptomics to measure drivers of senescence and fibrosis on a cellular level within diseased human heart tissue.Your skills and attributes for success:

• A PhD or equivalent professional qualification and/or experience in the field of biological sciences and/or bioinformatics.
• Experience in bioinformatic analyses of complex datasets.

and / or

• Experience of in vitro cell culture &
• Experience in various techniques such as RNA extraction, immunohistochemistry, microscopy etc.
• Strong planning and organising skills.

Click to view a copy of the full (opens new browser tab)As a valued member of our team, you can expect:An exciting, positive, creative, challenging and rewarding place to work. We give you support, nurture your talent and reward success. You will benefit from a competitive reward package and a wide range of staff benefits, which includes a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, flexible working and much more. Check out the full list on our (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa. Please note if the role is offered on a part-time basis, it may result in sponsorship being dependent on a number of factors specific to the successful applicant or the role no longer meeting the Home Office’s criteria for sponsorship.Key notes for applicantsAs part of this application, you are required to upload a cover letter/statement of not more than one page detailing how you meet each of the essential criteria as outlined on the job description and a CV. These items should be uploaded as one single combined document in either PDF or Word format.The closing date for applications is 17th June 2025.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.We anticipate that interviews will be held within 2-3 weeks of the advert closing date.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Inflammation Research (CIR; Director, Professor David Dockrell) leverages peer-reviewed interdisciplinary research programmes and focussed collaboration, to characterise mechanisms of acute and chronic inflammation. CIR aims to characterise what promotes health at the molecular level in order to prevent the harmful consequences of inflammation in clinical medicine. Effort is targeted at: inhibiting the initiation of inflammation by blocking specific molecular triggers and by modulating cellular and tissue responses resulting in organ dysfunction; finding new approaches to modulate established inflammatory responses to limit tissue injury; and promoting safe resolution of inflammation to restore healthy structure and function of tissue.The CIR has a broad interest in inflammatory disease in a range of tissues including in the lungs, kidney, liver, pancreas, bowel, bone, joints, skin, heart and brain. There is in-depth analysis of stimuli that induce or modify inflammation with detailed programmes considering the role of sex, development, auto-immunity, infection and other environmental influences. Importantly, the principles derived will have ready application to inflammatory and reparatory responses in virtually all physiological and pathological settings, including cancer and infection (not least COVID-19). Translation is aided by a commitment to novel diagnostic and imaging modalities and our proximity to patient groups and healthy volunteers in the Royal Infirmary, Edinburgh.Our research aims align closely with the vision of IRR and other centres within IRR, to promote human health through in-depth understanding of tissue regeneration and repair, while developing a multi-pronged translational programme to effect therapeutic innovation in this area. IRR is located on the BioQuarter Campus, Edinburgh.

Expected salary

£40497 – 48149 per year

Location

Edinburgh – Midlothian

Job date

Thu, 29 May 2025 03:31:01 GMT

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